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Even though your body may have adapted to GLP-1 receptor activation from a previous peptide, the glucagon receptor activation in retatrutide is entirely new

GLP-1s have become first-line therapy for type 2 diabetes Traditionally, the first-line treatment for newly diagnosed type 2 diabetes has been inexpensive generics, but that is changing

Semaglutide is injected once weekly using a small, thin needle into the abdomen, thigh, or upper arm

Potential side effects include an increased likelihood of cholecystectomy due to gallbladder disease, a higher risk of aspiration pneumonia from intestinal obstruction and delayed gastric emptying, and a potential for pancreatitis

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