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Compared with lifestyle changes or older anti-obesity medications, our study in Obesity showed that GLP-1 receptor agonist regimens are superior for treating weight regain after bariatric surgery

25,26 Effects on Epicardial Adipose Tissue GLP1-RAs decrease the volume of epicardial adipose tissue, which is often elevated in HFpEF and is a source of proinflammatory cytokines and adipokines

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As more patients enter the OR and ICU with a history of GLP-1 use, our study provides a vital first look at how these drugs might be "priming" the immune system for better resilience