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Sam has published in the New York Times, Washington Post, Boston Globe, Time Magazine, and other outlets

They also adjusted for factors that could potentially skew the results, such as age, sex and how long they'd had diabetes

The mean change in body weight from the switch point was minus 0.1 kg with orforglipron, compared to plus 9.4 kg with placebo at 24 weeks

A 2024 study led by Wang, Volkow, and colleagues examined two cohorts totaling over 682,000 individuals with either obesity or type 2 diabetes and found the risk of new alcohol use disorder diagnoses was about 50% lower among those taking semaglutide compared to other anti-obesity or diabetes medications (Wang et al., 2024a)

Targeting GLP-1 Receptors As we mentioned above, Semaglutide belongs to the class of glucagon-like peptide-1 (GLP-1) receptor agonists

But the study also raises important questions