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In addition to GLP-1 medications, a class of medications used in type 2 diabetes called SGLT-2 inhibitors is also being studied for use with type 1 diabetes
nausea, vomiting, diarrhoea, and constipation) are common [3, 5], serious adverse effects (e.g
FIGURE 17 5 Conclusion The expression of GLP-1R in tissues other than the pancreas, such as the brain, endocrine tissues, heart muscle, kidneys, lungs, muscle, and vascular tissues, as well as the proximal digestive and gastrointestinal tract, indicates that GLP-1 has a multifaceted regulatory role beyond glucose homeostasis mediated by insulin release
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4,24 In clinical trials thus far, GLP-1 agonists have shown their weight-loss effects only in conjunction with diet and exercise
