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Between 2025 and 2030, the global pharmaceutical industry faces a Loss of Exclusivity (LOE) wave that puts an estimated $200 billion to $400 billion in branded drug revenue at direct risk.

New real-world research presented at the AAAAI Annual Meeting suggests that glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may significantly reduce asthma exacerbations in overweight and obese adults without diabetes pointing to a potential new therapeutic strategy for a difficult-to-treat population.

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Glucagon-like peptide-1 agonist drugs have been surging in popularity, and manufacturers are scurrying to keep up with demand

World Obesity Federation, World Obesity Atlas 2023 Unsurprisingly, weight loss medications have captured innovators attention as potential solutions, however, the obesity market has a history of many false dawns, as drugs in the past failed to deliver meaningful efficacy while some had serious safety issues, e.g., Fen-Phen, which was eventually withdrawn from the market due to cardiac risks3