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Description
This may have resulted from the timing of the study relative to the COVID-19 pandemic (SURMOUNT-1 and STEP during, ONeil and SCALE Obesity and Prediabetes prior), which may have impacted the reporting of safety events

Larger injection volumes create more pressure in the subcutaneous tissue, which can cause more discomfort and a higher chance of lumps or the medication leaking back out

Adults who have type 2 diabetes could use it to control their blood sugar better

SURMOUNT-1: the landmark trial This 72-week trial enrolled 2,539 adults with obesity (BMI 30 or higher) or overweight (BMI 27 or higher) with at least one weight-related comorbidity

Patients experiencing significant nausea may benefit from evening injections, allowing them to sleep through the period of peak medication absorption

However, both McGowan and Dr
