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This may have resulted from the timing of the study relative to the COVID-19 pandemic (SURMOUNT-1 and STEP during, ONeil and SCALE Obesity and Prediabetes prior), which may have impacted the reporting of safety events

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Larger injection volumes create more pressure in the subcutaneous tissue, which can cause more discomfort and a higher chance of lumps or the medication leaking back out

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Adults who have type 2 diabetes could use it to control their blood sugar better

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SURMOUNT-1: the landmark trial This 72-week trial enrolled 2,539 adults with obesity (BMI 30 or higher) or overweight (BMI 27 or higher) with at least one weight-related comorbidity

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Patients experiencing significant nausea may benefit from evening injections, allowing them to sleep through the period of peak medication absorption

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However, both McGowan and Dr

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