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However, kidney and heart protection are not fully explainable by the metabolic actions of these agents
In an ideal case, such co-administration would engage complementary signaling mechanisms such that the magnitude of metabolic benefits might be even greater than the sum of the individual monotherapies i.e., producing synergy

Common and Serious Side Effects of Mounjaro You may get both common and serious side effects when you use Mounjaro

Clinical trials with tirzepatide demonstrate that GIP agonism combined with GLP-1 agonism is safe and effective for weight loss
Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications primarily used to manage type 2 diabetes and, more recently, obesity

Nutrition Journal , 10(1), 93