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External resources New England Journal of Medicine: Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1) PubMed Central: Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity For researchers serious about optimizing their peptide protocols and navigating the rapidly shifting vendor landscape, SeekPeptides offers the most comprehensive resource available

Moreover, some of the impressive metabolic gains from bariatric surgeries have been ascribed to alterations in the secretory profile of gut hormones

the proportion who said their thoughts about food had negative effects on them or their life fell from 60% to 20%

Effective contraception is essential during treatment, as GLP-1 medications are not recommended during pregnancy and semaglutide requires a 2-month washout period before conception

GLP-1 receptor activation has been associated with improved endothelial function in some studies

Uncommon (may affect up to 1 in 100 people) weight loss gallstones burping fast pulse allergic reactions like rash, itching or hives