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If irritation occurs, consult with your healthcare provider

If pediatric use is needed, liraglutide is currently the only option with regulatory approval for adolescents aged 12-17
The cost of retatrutide through research suppliers currently runs higher per milligram than compounded tirzepatide, largely because of limited manufacturing scale and the absence of compounding pharmacy competition

This is not specific to retatrutide but occurs with any significant caloric deficit

Eating smaller, more frequent meals instead of large portions reduces the burden on a slowed digestive system