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Summary: GLP-1 receptor agonists can cause gas and bloating by slowing gastric emptying, which prolongs food transit through the digestive tract and increases bacterial fermentation
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D., Joly, E., Horsmans, Y

Blockade of either the central or peripheral GLP-1R attenuates GLP-1induced satiation (60, 69, 70)

Factors That Influence How Fast GLP-1 Works Individual response to GLP-1 medications varies considerably , and several factors influence both the speed and magnitude of therapeutic effects

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