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There was also a significant decrease in the VAT area (32.31 cm)

Furthermore, a meta-analysis of data from large cardiovascular outcome trials (CVOT) demonstrates that GLP-1RA therapy does not seem to elevate the risk of pancreatic cancer in patients with T2DM [7]

In the 2022 SURMOUNT-1 study published in NEJM, three doses of tirzepatide were compared with placebo (1:1:1:1) to determine effects on percent weight change over the course of 72 weeks

10.2337/dc23-S009

Similar to the alcohol-related responses, GLP-1R within the NTS, LDTg, VTA, and NAc modulates the behavioral responses induced by cocaine

A Phase III clinical trial of exenatide (again, the Bydureon formulation) is now underway at 6 sites in the UK ( Click here to read more about this)
