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These symptoms often correlate with other gastrointestinal effects and typically improve as tolerance develops

Some studies see evidence of improvements as early as eight weeks, and in long-term follow-up, patients gained back over 5% of lost weight 15 years after reaching their lowest weight

Restless Legs Syndrome and Parkinson Disease: A Causal Relationship Between the Two Disorders

J Neurosci Res 72(5):603612 Baggio LL, Drucker DJ (2007 May) Biology of incretins: GLP-1 and GIP

[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Abdali D., Samson S.E., Grover A.K

Gregg E, Jakicic J, Blackburn G et al (2016) Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial