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This review highlights cutting-edge neurobiological tools such as optogenetics, chemogenetics and imaging that enable precise dissection of brain metabolism interactions, advancing our ability to study and treat metabolic aspects of eating disorders

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Semaglutide is a once weekly injectable (and oral formulation) medication originally developed for the treatment of type 2 diabetes

Here we report high-resolution cryo-electron microscopy (cryo-EM) structures of human GLP-1RG s in complex with compound 2 alone, with both compound 2 and endogenous peptidic agonist GLP-1, or with compound 2 and a small molecule agonist (LY3502970)

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