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Trials such as PADA-1 have explored switching endocrine therapy in response to rising ESR1 mutations detected in circulating tumor DNA, suggesting a potential for real-time monitoring and adaptive therapy

GLP-1 for Diabetes If you are using a GLP-1 for diabetes management, do not stop the medication without speaking to your doctor first
Sci Transl Med 5:209ra151 Finan B, Yang B, Ottaway N et al (2015) A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

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Moderate alcohol consumption is generally safe, but excessive drinking may worsen nausea or increase the risk of hypoglycaemia