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Since tirzepatide is a once-weekly injection, rotate between your right and left thigh every two weeks, then vary the injection position (upper, middle, lower) within each thigh across a four-week cycle

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If the powder looks off, do not reconstitute it

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That depends on your concentration

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10.4158/EP161365.GL 17 GourgariE.WilhelmE

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Meal timing around injection day Most tirzepatide users find that GI side effects are most pronounced in the 24 to 48 hours following their weekly injection

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The slowed gastric motility that reduces appetite also slows transit through the entire digestive tract

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