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Efficacy and safety of high-dose glucagon-like peptide-1, glucagon-like peptide-1/glucose-dependent insulinotropic peptide, and glucagon-like peptide-1/glucagon receptor agonists in type 2 diabetes

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Key Considerations Before Combining Metformin and Semaglutide If you have type 2 diabetes or prediabetes and are already taking metformin, adding semaglutide can amplify weight loss and improve cardiovascular markers