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A new dosage or potency A new drug combination, such as semaglutide mixed with vitamin B12 A new drug form, such as a liquid or pill rather than an injection Brunner thinks clinicians will increasingly take advantage of these exceptions: I think we'll see more prescribers move into the customized dosage side of compounding. Custom Dosages This customization has also fueled interest in microdosing GLP-1s, a technique in which patients take smaller amounts to try to achieve gradual weight loss or minimize side effects

While rodent data support continued caution in MTC, GLP-1RAs should not be regarded as an absolute contraindication in other thyroid cancer subtypes, provided that treatment is individualized and appropriate monitoring is undertaken

doi: 10.2337/dc17-S011 2

Ozempic is a GLP-1 receptor agonist that signals fullness and reduces appetite, while metformin is a biguanide that primarily improves insulin sensitivity
