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Comprehensive evaluation of a levonorgestrel intrauterine device (LNG-IUD), metformin, and liraglutide for fertility preservation in endometrial cancer: protocol for a randomized clinical trial

Remarkably, the 15 mg dose of tirzepatide decreased HbA1c by 2.46% and body weight by 12.4 kg at the end of the study

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They function as insulin sensitizers by activating the peroxisome proliferator-activated receptor gamma (PPAR-), a type of nuclear receptor that plays a crucial role in the regulation of glucose and lipid metabolism

Finan B, Ma T, Ottaway N, et al