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Targeting the GLP-1/GLP-1R Axis to Treat Osteoarthritis: A New Opportunity
4 Clinical evidence In adults with obesity, 72 weeks of orforglipron treatment resulted in greater body-weight reductions than placebo, up to -11.2%, compared to -2.1% with placebo

Diabetes (2007) 56:19519

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It's a great tool for crushing high food noise but that's literally all it can do (on paper anyway)

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