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Furthermore, there was no differential impact of treatment (versus placebo) on metabolic parameters in MC4R mutation carriers versus noncarriers (Extended Data Table 3)

Obesity is a chronic, progressive disease, and sustaining weight loss remains a significant challenge for many, Kenneth Custer , PhD, executive vice president and president of Lilly Cardiometabolic Health, said in a statement

But calculators eliminate the possibility of arithmetic errors, which is especially valuable when you are dealing with medications where mistakes have real consequences

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As with many drugs, it is important to be aware of the potential side effects associated with its use

Sometimes it's a sign that something else, like unmanaged reflux or a bacterial overgrowth, needs attention