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Henney 2024) demonstrated a potentially meaningful reduction in incident pneumonia with GLP-1 RAs compared with dipeptidyl peptidase-4 (DPP-4) inhibitors (hazard ratio [HR] 0.60, 95% confidence interval [CI] 0.580.62

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The study was led by first author Dr Sudipta Sen, associate professor, and senior author and Professor Omonele Nwokolo, both from the Department of Anesthesiology, Critical Care and Pain Medicine at McGovern Medical School at UTHealth Houston."Our findings were quite surprising

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Their lead candidate, ECC5004, is an oral GLP-1 agonist licensed to AstraZeneca for global development (excluding China), while Eccogene retains co-development and co-commercialization rights in China

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