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Clinical trials have shown Tirzepatide can produce greater weight loss results, up to 22.5% body weight reduction, compared to single-action GLP-1 medications

Amylin decreases meal size in rats

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Transl Psychiatry 3:e263 Fan X, Diao W, Wang H, Yin X, Qian W (2025) Interferon regulatory factors as a potential therapeutic target for neuroinflammation: a focus on Alzheimers disease

That dual action may give the drug a bit more juice