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In a pool of two ZEPBOUND clinical trials for weight reduction (Studies 1 and 2), cholelithiasis was reported in 1.1% of ZEPBOUND-treated patients and 1% of placebo-treated patients, cholecystitis was reported in 0.7% of ZEPBOUND-treated patients and 0.2% of placebo-treated patients, and cholecystectomy was reported in 0.2% of ZEPBOUND-treated patients and no placebo-treated patients

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The recommended injection sites include the abdomen (at least two inches from the navel), the front of the thigh, and the back of the upper arm

As with any Zepbound side effects, if your stomach problems or indigestion get worse, Decotiis says to talk with your health provider and work on a solution

While tirzepatide dramatically reduces hunger, some researchers still consume calorie-dense low-nutrient foods when they do eat

Adding too little water creates an overly concentrated solution