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Phentermine, the stimulant component of Qsymia, can increase heart rate and is generally avoided in patients with significant cardiovascular disease

Currently, there is limited interest in the non-GLP-1R obesity field, as sales for obesity drugs targeting alternative mechanisms are only forecast to generate a mere $310m in 2026

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( 10.2337/dc14-1958) [DOI] [PubMed] [Google Scholar] 36.Jensen EP, Poulsen SS, Kissow H, Holstein-Rathlou NH, Deacon CF, Jensen BL, Holst JJ, Sorensen CM

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