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University of Washington, Seattle, Seattle (WA (1993)

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The process differs meaningfully between brand-name and compounded medications, and knowing the details ensures a smooth experience from prescription to first injection

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Average weight loss was ( 7.8 pounds (3.55 kg) for a 3.75/23 mg (phentermine/topiramate) dose 16 pounds (7.27 kg) for a 7.5/46 mg dose 18 pounds (8.25 kg) for a 15/92 mg dose In users of phentermine-topiramate, weight loss translated to a significant decrease in waist circumference as well as improved insulin sensitivity, improved blood sugar management, and reduction in blood pressure ( May be helpful for certain eating disorders The combination of phentermine and topiramate may help reduce binge eating in people with BED and bulimia nervosa

After 30 days, it increases to 7 mg daily, and may be increased to the maximum dose of 14 mg daily after another 30 days