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Subcutaneous administration of pegbelfermin over 16 weeks was generally well tolerated and significantly decreased hepatic fat fraction based on MRI in MASH subjects during a phase 2 study (NCT02413372)

"Our results point to a future where we can improve metabolic health without losing muscle mass," said paper co-author and Stockholm University molecular biologist professor Tore Bengtsson in a statement

Moderation is advisable, and some men choose to eliminate alcohol entirely during active weight loss phases
The most common effects are mild and temporarynausea, early fullness, constipation, or heartburn

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