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In this review, we discuss the clinical trials, efficacy, United States FDA-approved indication, contraindications, and serious side effects of different classes of drugs, including lipase inhibitors, GLP-1 agonists, leptin analogs, and MC4R agonists.

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Rapid weight loss from Semaglutide (Ozempic/Wegovy) can cause 'Ozempic Face' and body sagging