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The vial is sold as an analytical reference compound with COA-grade documentation rather than as a patient-ready preparation, and the price reflects synthesis, purification, and third-party release testing rather than pharmacy compounding margins, prescription handling, or dispensing labour

Key Points Revisional metabolic and bariatric surgery (RMBS) leads to significantly greater weight loss than semaglutide at 2-year follow-up

These data highlight the limited reversibility of established cirrhosis and suggest that metabolic improvement alone may be insufficient to remodel advanced fibrosis within typical trial durations

While most semaglutide injection site reactions are benign and self-limiting, certain presentations require prompt medical evaluation to rule out complications or hypersensitivity reactions