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However, behavioral programs typically produce 510% weight loss, while GLP-1 medications average 1522%

25 mg daily from day 91 (maintenance dose)

These might include gastro-oesophageal reflux (which is a recognised side effect), changes in eating patterns, or indirect effects related to the medication's impact on gastrointestinal function

However, if weight loss plateaus after 46 weeks or remains below 3%, dose escalation is typically recommended to engage higher levels of receptor saturation

Clinical implications of the study results Significant improvement in albuminuria with Tirzepatide treatment observed in the SRM has multiple important clinical implications

It is often used as a comparator peptide when characterising newer molecules such as Retatrutide or Cagrilintide combinations