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Conclusion: These data indicate that GLP-1 analogs can exert significant anti-inflammatory effects on CSMCs and can potentially be used as an adjunct treatment for inflammatory bowel conditions

"Tirzepatide is approved for sleep apnea and is undergoing clinical trials for other indications." Based on his own clinical experience, Osborn reiterated that in many cases, tirzepatide is a "superior agent." "Its a dual incretin, meaning it targets two biochemical pathways," he told Fox News Digital
[DOI] [PubMed] [Google Scholar] 22.Incretin hormones: their role in health and disease
Regul Pept 1563:7076

10 You might also gain weight if you're not getting enough sleep or are on certain medications for example, some prescriptions used to combat hormone-related menopause symptoms can contribute to weight gain

While this risk has not been confirmed in human epidemiological studies, patients with personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should not use orforglipron or any GLP-1 receptor agonist
