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It is a dual GIP/GLP-1 receptor agonist, meaning it activates two incretin pathways simultaneously

The Cochrane Collaboration Risk-of-Bias tool was used for quality assessment of the RCTs [18], including sequence generation, allocation concealment, blinding, incomplete outcome data, and selective outcome reporting

6 ADVERSE REACTIONS The following serious adverse reactions are described below or elsewhere in the prescribing information: Risk of Thyroid C-cell Tumors [see Warnings and Precautions (5.1)] Acute Pancreatitis [see Warnings and Precautions (5.2)] Diabetic Retinopathy Complications [see Warnings and Precautions (5.3)] Hypoglycemia with Concomitant Use of Insulin Secretagogues or Insulin [see Warnings and Precautions (5.5)] Acute Kidney Injury Due to Volume Depletion [see Warnings and Precautions (5.6)] Severe Gastrointestinal Adverse Reactions [see Warnings and Precautions (5.7)] Hypersensitivity Reactions [see Warnings and Precautions (5.8)] Acute Gallbladder Disease [see Warnings and Precautions (5.9)] Pulmonary Aspiration During General Anesthesia or Deep Sedation [see Warnings and Precautions (5.10)] 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

Effect of dapagliflozin on glycemic control, weight, and blood pressure in patients with type 2 diabetes attending a specialist endocrinology practice in canada: a retrospective cohort analysis

The tirzepatide levocarnitine blend is a compounded medication that combines two distinct ingredients into a single injectable formulation

doi: 10.4093/dmj.2023.0277 [DOI] [PMC free article] [PubMed] [Google Scholar] 47.Asplin JR