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In addition to the 5-HT DRN neurons, dopaminergic neurons in the VTA (DA VTA ), also receive dense projections from orexin neurons originating from the lateral hypothalamus (LH) and dorsal medial hypothalamus

It affects two hormones, leading to significant weight loss and lower blood glucose

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A new generation of oral tablets, multi-target agonists, and next-generation injectables is reshaping the competitive landscape at pace, with fresh regulatory approvals, pivotal Phase 3 data, and an expanding list of indications that stretches far beyond weight loss and type 2 diabetes