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Mediating role of bone marrow lesions, synovitis, pain sensitization, and depressive symptoms on knee pain improvement following substantial weight loss
Devanarayan V, Smith WC, Brunelle RL, Seger ME, Krug K, Bowsher RR
In many disease states, such as metabolic syndrome, inflammatory bowel disease (IBD), cardiovascular diseases, malignant tumors, etc., the structure and function of intestinal microbiota are obviously different from those of healthy bowel microbiota (Tilg and Moschen, 2014
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Weight and ectopic-fat reduction (the dominant, indirect route)
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