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Excess macronutrients in adipose tissues trigger the release of inflammatory mediators, including leptin, tumor necrosis factor-, and interleukin-6, while decreasing the production of adiponectin (an anti-inflammatory adipokine), predisposing to a pro-inflammatory state and oxidative stress

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Food and Drug Administration, 2023b), which could include some products advertised as compounded semaglutide

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(2022, March 18)

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This study used clinical EHR data, which has some inherent limitations

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