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Platycodin d inhibits diabetic retinopathy via suppressing TLR4/MyD88/NF-B signaling pathway and activating Nrf2/HO-1 signaling pathway

November 2025: Boehringer Ingelheim licensed a novel GLP-1 analogue candidate from a research partner to advance its pipeline for type 2 diabetes and obesity indications
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In addition, insulin resistance contributes to systemic inflammation and oxidative stress, both of which can impair spermatogenesis

However, no head-to-head comparisons of GLP-1RAs and other non-insulin glucose-lowering medications exist for patients with NAFLD and type 2 diabetes
2018;175(2):47287e20
