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As stated in the MHRA SmPC, Mounjaro must be discontinued permanently if pancreatitis is confirmed

Side Effects Common Headache Nausea, vomiting Abdominal pain Constipation or diarrhea Bloating / flatulence Long-Term or Serious Vitamin B12 deficiency Hypomagnesemia Increased risk of fractures (hip, spine, wrist) Kidney injury (interstitial nephritis) C

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Key Considerations Before Combining Metformin and Semaglutide If you have type 2 diabetes or prediabetes and are already taking metformin, adding semaglutide can amplify weight loss and improve cardiovascular markers