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Both GIP and GLP-1 are primarily secreted by enteroendocrine cells within the intestines after nutrient ingestion

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No single hormone has to be pushed to an extreme, which is part of why tolerability held up reasonably well even at the top dose

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After two years, patients who had surgery lost an average of 25.7 percent of their total body weight

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Beyond oncology, microenvironmental heterogeneity also impacts the development and efficacy of GLP-1R-targeted nanomedicines across a wide range of diseases

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