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The combination of these two drugs aims to leverage their complementary mechanisms, maximizing weight loss and metabolic control

For signs of infection at the injection site (rapidly spreading redness, warmth, swelling, or pus) or systemic symptoms such as high fever, chills, or feeling severely unwell, contact NHS 111 or attend an urgent treatment centre promptly

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If you experience dry mouth or other changes, you can reach out for guidance on how to manage them effectively

In 1 of the RCT trials, semaglutide lowered body weight by 5.0 kg from baseline, primarily by reducing body fat mass [30]

Improvements in testosterone in obese patients is often attributed to weight management and potentially involving changes in insulin sensitivity, inflammation, and restored hypothalamic-pituitary-gonadal axis function