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Serious adverse events reported in temporal association with GLP-1 RA exposure included anaphylaxis with bronchospasm (n=4 cases), acute eosinophilic pneumonia (n=1), perioperative aspiration pneumonitis or pneumonia (multiple perioperative cases across two cohort studies and one case series), acute respiratory distress syndrome (ARDS
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Disclosure (personal): I had the privilege of serving as a Principal Investigator for the SURPASS-CVOT trial
PlexusDx personalized semaglutide protocols account for individual cardiovascular tolerance
However, healthy human C-cells express few to no GLP-1 receptors making this risk largely theoretical
28.7% vs 22.5% vs 15% Phase 3 data compared
