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The focus should remain on tolerability rather than achieving the maximum dose
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PubMed Aminian, A., Zajichek, A., Arterburn, D.E., Wolski, K.E., Brethauer, S.A., Schauer, P.R., et al

Pearson TA, Mensah GA, Alexander RW et al (2003) Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the centers for disease control and prevention and the American Heart Association

According to the Medicines and Related Substances Act, 101 of 1965, as amended, compounding must remain strictly within the applicable parameters of the law and cannot be used as a mechanism for large-scale manufacture, advertising, or distribution of unregistered medicines
