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503A pharmacies are required to comply with FDA rules, regulations, and guidance, among other applicable laws, rules, regulations, and guidance

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A 2019 Phase 2 dose-escalation study compared three different titration algorithms over 12 weeks and found that slower escalation reduced gastrointestinal events without losing efficacy at the target maintenance dose

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For example, instead of three larger meals consumed five hours apart, try three small meals and two snacks spread two or three hours apart

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