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Science 359 , 10421046 (2018)

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The SURMOUNT-1 trial evaluating tirzepatide demonstrated substantial results, with participants achieving mean weight reductions of approximately 15% (5 mg), 19.5% (10 mg), and 20.9% (15 mg) over 72 weeks

Misconceptions about the efficacy and safety of GLP-1 receptor agonists can lead to reluctance in prescribing or taking these treatments

Enhance insulin secretion Stimulates insulin release only when blood glucose is high
