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2010 Apr;151(4):1473-86 Madsen LW, Knauf JA, Gotfredsen C, Pilling A, Sjgren I, Andersen S, Andersen L, de Boer AS, Manova K, Barlas A, Vundavalli S, Nyborg NC, Knudsen LB, Moelck AM, Fagin JA
doi: 10.1139/h2012-068
Researchers compared the percentage of body weight loss after 3, 6, 9 and 12 months of treatment among adults who received intensive lifestyle modification, non-GLP-1 receptor agonist pharmacotherapy or GLP-1 receptor agonists as part of a weight-loss program, with both pharmacotherapy groups also utilizing intensive lifestyle modification
Most patients regain weight after stopping GLP-1 medications, with clinical trials showing approximately two-thirds of lost weight returns within one year
The physiological changes that accompany GLP-1 therapy can create conditions where tiredness becomes more noticeable
The final selection of references reflects a comprehensive and multidisciplinary synthesis to inform both dermatologic and surgical practice
