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GLP-1 has opposing effects on hepatic lipid accumulation and plasma lipid levels, which has recently broadened its clinical use in pharmacological therapy of metabolic syndrome and steatohepatitis 8,9

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GLP-1 fatigue affects roughly 5 to 11 percent of users in clinical trials

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Once-weekly subcutaneous semaglutide treatment for persons with type 2 diabetes: Real-world data from a diabetes out-patient clinic