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Description
The absence of an effect on psoriasis vulgaris suggests that SGLT2i may preferentially modulate joint-specific inflammation (enthesitis, synovitis) rather than skin inflammation, possibly through effects on entheseal resident cells or mechanical stress pathways

Medi-Cal Rx has announced exclusion effective Jan 1, 2026

10 Thiazolidinediones (TZDs): These drugs (e.g., rosiglitazone, pioglitazone) exert their effect through the peroxisome proliferator activated receptor- (PPAR)

Trulicity and Wegovy appear to have similar safety profiles
How we grade evidence [1] Moiz A, et al

Back Tu, L (16 Oct 2023) 'Should insurance cover Wegovy, Ozempic and other weight-loss drugs?', Scientific American
