jama glp 1 Glucagon-like peptide-1 (GLP-1) receptor agonists (semaglutide [Wegovy, Ozempic, Rybelsus]) and dual incretin agonists (tirzepatide [Zepbound, Mounjaro]) are medications that reduce food cravings, increase fullness, slow digestion, and can help control GLP-1 drugs can help you

Tirzepatide displayed an unprecedented glucose and body weight lowering potential, presenting also with the ability to increase insulin sensitivity, reduce systolic blood pressure and inflammation and ameliorate dyslipidemia, particularly by reducing triglycerides levels

An editorial review of Bioverse: program structure, compounded-pharmacy pathway, pricing, and safety considerations

Whether its GLP-1 receptor agonists or the new generation of GLP-1 therapies, one thing remains critical

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If GLP-1s do what the evidence suggests they will do, this will be one of the clearest demonstrations in modern psychiatry of why we fund preclinical research and why translational pipelines matter

Looking ahead, the influence of US policy and Most Favoured Nation (international reference) pricing will remain a central trend that shaped obesity care in 2025 and will continue to do so into 2026 and beyond