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Its all critical, very important and a major contribution to the science, he said

Nausea, diarrhea, and digestive discomfort occur somewhat more frequently with tirzepatide than with semaglutide

doi: 10.3389/fneur.2019.00493

The 2 retatrutide Phase 2 trials are summarized graphically below, links here and here

These specialized immune cells express GLP-1 receptors and when GLP-1(whether from native production or GLP-1 agonists) activates these IELs via GLP-1R it helps to suppress localized T-cell induced inflammation

If Phase 3 trials complete successfully and Lilly submits an NDA in late this year, FDA approval could come by mid to late next year
