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Bull FC, Al-Ansari SS, Biddle S, Borodulin K, Buman MP, Cardon G, et al

However, these proteins were in circulation for only a short time, limited to 1-2 minutes, due to their degradation by the enzyme dipeptidyl peptidase-4 (DPP-4), which raised questions regarding use of GLP-1s as pharmaceutical treatments [9]

Manufacturers must invest in early benchtop process development to model and optimize their continuous chromatography system, ensuring its right-sized to keep pace with intensified upstream operations

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