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Additionally, GLP-1 also demonstrates significant appetite suppression and delays gastric emptying, making it an effective candidate drug for the treatment of type 2 diabetes and obesity

GLP-1 suppresses feeding behaviors and modulates neuronal electrophysiological properties in multiple brain regions

This becomes even more complex as brands also look to reduce sugar, which can further impact taste, mouthfeel and overall enjoyment." Balancing protein, fiber, reduced sugar and overall enjoyment requires thoughtful formulation, the senior food scientist adds

Moreover, GLP-1 upregulated BV2 microglia cells expression of BDNF in a PKA-dependent manner (184)

8 Therefore, given the increasing burden of lean MASLD in some populations and the benefits of GLP-1RA in weight management, more clinical attention is warranted