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The hippocampus, a brain structure associated with memory formation, seems to be particularly affected in depression [43, 44]

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Conclusion GLP-1R agonists have revolutionized diabetes and obesity management , but their role in perioperative care remains complex

They are also not recommended in individuals with certain conditions such as inflammatory bowel disease, pancreatitis, personal or family history of medullary thyroid cancer or multiple endocrine neoplasia

Patients should seek urgent medical attention for severe or persistent abdominal pain, repeated vomiting, or signs of dehydration, as these may indicate pancreatitis or gallbladder disease

A study of 604 adults evaluated the impact of a weight loss program which included a diet of approximately 1200 kcal/day and self-moderated exercise with the goal of 150 min of moderate activity per week over 15 weeks